Modification of natural hydrocolloid as disintegrant in aceclofenac tablet formulation
نویسندگان
چکیده
منابع مشابه
Evaluation of Abelmoschus starch as tablet disintegrant
Seed starch (16.0%w/w) obtained from Abelmoschus moschatus Linn. (Malvaceae) was employed as a disintegrant to paracetamol tablets at concentrations of 2.5-10.0% w/w. The granules prepared by wet granulation technique were evaluated for percentage of fines and flow properties. Tablet properties including thickness, content uniformity, average weight and weight variation, hardness, friability, d...
متن کاملNatural Binding Agents in Tablet Formulation
Binders are agents employed to impart cohesiveness to the granules. This ensures the tablet remains intact after compression. The development of new excipients for potential use as binding agent in tablet formulations continues to be of interest. This is because different binding agents can be useful in achieving various tablet mechanical strength and drug release properties for different pharm...
متن کاملEstimation of Paracetamol and Aceclofenac in Tablet Formulation by Ratio Spectra Derivative Spectroscopy
A new sensitive, simple, rapid and precise method for simultaneous estimation of paracetamol and aceclofenac in combined tablet dosage form has been developed. The method is based on ratio derivative spectrophotometry. The amplitude in first derivative of the ratio spectra at 256 nm and 268 nm (minima) were selected to determine paracetamol and aceclofenac in combined formulation. The method sh...
متن کاملEffects of modification and incorporation techniques on disintegrant properties of wheat (Triticum aestivum) starch in metronidazole tablet formulations.
BACKGROUND Natural polymers serve as cheap, non-toxic, biocompatible excipients in drug delivery. OBJECTIVES Starch from wheat (Triticum aestivum) was investigated as a disintegrant in metronidazole tablet formulations in comparison with sodium starch glycolate (SSG), a standard, synthetic but relatively more expensive disintegrant. MATERIAL AND METHODS Native wheat starch (NAS) was modifie...
متن کاملFormulation Design of Fast Disintegrating Tablets Using Disintegrant Blends
In the present work, fast disintegrating tablets of prochlorperazine maleate were designed with a view to enhance patient compliance by direct compression method. In this method, crospovidone (up to 3% w/w) and croscarmellose sodium (up to 5% w/w) in combination were used as superdisintegrants. Since disintegrants complement each other, accelerating the disintegration process when used together...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2021
ISSN: 2250-1177
DOI: 10.22270/jddt.v11i2.4586